question_answer 20)

  Match the following column of bioactive substances and their roles.  

Column I(Bioactive)	Column II(Role)
A.  Statin B.  Cytosporin A C.  Streptokinase D.  Lipase	1. Removal of oil stains 2. Removal of clots from blood vessels 3. Lowering of blood cholesterol 4. immune-suppressive agent

  Codes A             B             C             D (a)          2              3              1              4 (b)          4              2              1              3 (c)           4              1              3              2 (d)          1              2              3              4

Answer:

                  (d) Following is the column of bioactive substances and their roles  

Column I(Bioactive)	Column II(Role)
A.  Statin B.  Cytosporin A C.  Streptokinase D.  Lipase	Lowering of blood cholesterol Immune-suppressive agent Removal of clots from bloodvessels Removal of oil stains

  Statins produced by the yeast Monascus purpureus have been commercialized as blood cholesterol lowering agents. Cyclosporin A, produced by the fungus Trichodermapolysporurn is used asanimmuno suppressive agent in organ transplant patients. Streptokinase produced by the bacterium Streptococcus and modified by genetic engineering is used as a 'clot buster' for removing clots from the blood vessels of patients who have undergone myocardial infaction leading to heart attack. Lipases are used in detergent formulations and are helpful in removing oily stains from the laundry.