French chemist Louis Pasteur (1822-1895) was one of the truly brilliant minds of the nineteenth century, whose groundbreaking work in the field of microbiology and chemistry led to a long list of scientific discoveries. He is perhaps best remembered today for his development of "pasteurization" in milk, and the invention of a number of vaccines, including rabies, and anthrax. His discovery of a vaccination for cholera, however, was something of an accident, although he was aware of the work of Edward Jenner (1749-1823), who pioneered the smallpox vaccine.
In the summer of 1880, Pasteur was conducting experiments on chickens with cholera, and had instructed his assistant Charles Chamberland to inoculate the birds with a culture of cholera-bacteria. Chamberland failed to do so, and a month later the culture, which had now spoiled, was used of the birds. They became ill but did not die, so Pasteur introduced a new group
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